IBD studies
Studies open for participation
Crohn's Disease
VECTORS — Transmural Healing
An interventional study into customized treatment for patients with moderately to severely active Crohn's disease, focused on transmural healing.
POMEROL — Therapy escalation in post-operative recurrence
A randomized controlled trial that therapy escalation evaluates in patients with moderate postoperative recurrence of Crohn's Disease.
OATS — FIT Diet and Biological Therapy
A study into the combination of FIT diet with biologytherapie in patients with Crohn's disease.
Soprano — Prevention of post-operative recurrence
A multicentric study that demonstrates the systematic start of biological therapy immediately after a surgical resection compares with the more targeted start of biological therapy in patients with endoscopic injuries six months after surgery.
Ulcerative Colitis
AMETRINE 1 — RO7790121
A double-blind, placebo-controlled phase III study of the efficacy and safety of induction and maintenance therapy with RO7790121 in patients with moderately to severely active ulcerative colitis.
PASS-TOFA — Tofacitinib Safety
An active post-marketing surveillance study to investigate the Tofacitinib safety to characterize in the clinical practice of patients with moderately to severely active ulcerative colitis, based on data from the United Registries for Clinical Assessment and Research (UR-CARE).
ABTECT — Research into Obefazimod
A randomized, double-blind, placebo-controlled trial evaluating efficacy and safety of ABX464 (Obefazimod) once daily during induction and maintenance treatment in patients with moderately to severely active ulcerative colitis.
Future Studies
Crohn's Disease
OMICROHN — Crohn's Disease Treatment Selection Based on Epigenetic Markers
A prospective, randomized treatment selection trial in adults with the Crohn's disease, using epigenetic markers versus standard treatment.
ARES-CD — Evaluation of Tulisokibart
A randomized, double-blind, placebo-controlled trial evaluating efficiency and safety of Tulisokibart in patients with moderately to severely active Crohn's disease.
Crohn's Disease or Ulcerative Colitis
IMMUNO-IBD — Investigation of immune-mediated enterocolitis in IBD patients
A study into the natural history, risk factors, and incidence of immune-mediated enterocolitis in patients with inflammatory bowel disease (IBD) that are treated with immune checkpoint inhibitor (ICI) therapy.
AMARETTO — Subcutaneous Infliximab after previous dose optimization
A study on the use of subcutaneous Infliximab after a previous intravenous dose optimization in patients with Crohn's disease or ulcerative colitis.
